Intracellular lipid droplets support osteoblast function
نویسندگان
چکیده
منابع مشابه
Intracellular Lipid Droplets: From Structure to Function
Lipid droplets (LDs) are unique intracellular organelles that are mainly constituted by neutral lipids (triglycerides, sterol esters). As such they serve as the main site of energy storage in the cell and they are akin to oil emulsions in water. To prevent the direct exposure of the hydrophobic neutral lipids to the aqueous environment of the cytosol, LDs are surrounded by a monolayer of phosph...
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Lipid droplets (LDs) are ubiquitous but poorly understood neutral-lipid-rich eukaryotic organelles that may participate in functions as diverse as lipid homeostasis, membrane traffic, and signaling . We report that infection with the obligate intracellular pathogen Chlamydia trachomatis, the causative agent of trachoma and many sexually transmitted diseases , leads to the accumulation of neutra...
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Lipid droplets are intracellular organelles that play central roles in lipid metabolism. In many cells, lipid droplets undergo active motion, typically along microtubules. This motion has been proposed to aid growth and breakdown of droplets, to allow net transfer of nutrients from sites of synthesis to sites of need and to deliver proteins and lipophilic signals. This review summarizes the cur...
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A highly stable, long wavelength polarity sensitive probe, 8-nitrophenyl-3,5-dipiperidine-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (NPBDP), was developed for living cell imaging of intracellular lipid droplets by fluorescence microscopy.
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We report that the dye nile red, 9-diethylamino-5H-benzo[alpha]phenoxazine-5-one, is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytofluorometry. The specificity of the dye for lipid droplets was assessed on cultured aortic smooth muscle cells and on cultured peritoneal macrophages that were incubated with acetylated low density...
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ژورنال
عنوان ژورنال: Adipocyte
سال: 2017
ISSN: 2162-3945,2162-397X
DOI: 10.1080/21623945.2017.1356505